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"十全大补"来自科罗拉多大学生殖中心简称CCRM的一位著名医生，很多在那做IVF MM把这个"十全大补"贴到网上讨论，一位中国MM把它搬到海外华人第一名门网讨论（www.mittbbs.com)，但国内是看不到这个网的，用翻墙软件可以看到，所以我把最近大家讨论的十全大补复制给大家供参考。这个主要是提高卵子质量或对药物反应不好的MM也可以吃。* I( p R, y O- e# x/ l6 }+ [ z1 X9 V4 h
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4 v; z* ?8 ^$ W9 q0 ]“十全大补升级版”- Poor Responder Supplement( ^( q, p5 V2 x+ g* o( k3 ^
提高卵子质量的配方（antioxidant cocktail）$ b9 W" M, a+ F( v+ B- x' r8 `
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“十全大补（简版）”- 从下面的list去掉抗氧化剂L-arginine和Pycnogenol]
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医院对十全大补的建议是提前3个月进补。其最终效果，有时很明显，有时不太明显。: B" E) _; ?# p3 O7 h2 p! x6 I
不过，多吃无害。, N7 Z! {! G8 R+ D
( A5 B ~; N0 J7 F: |+ F; fhttp://www.mitbbs.com/clubarticle/IVF/31234253_0.html
* V! ]8 L- d3 L3 t2 |+ h! L要吃这个，最好是IVF3个月前开始，原因是，卵子从初始发育到最后排出，要经过3个月的历程，你3个月后用的卵子，是3个月前挑选发展的结果，所以这种十全大补，晚吃了就对要用的那批卵子作用很小了，虽然可能对整个生殖系统功能还是有正面意义。
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- copy from CCRM clinic - ! E* p/ n( d# ?2 B3 c4 B
=====================================
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+ [5 F- h5 N# \4 T& gPoor Responder Supplement! l. { B" @* l# ?; H# l; O8 Z
(Ideal supplementation 3 months prior to retrieval)1 _0 K" A" B/ P4 w, z1 @ f# x
# a7 j, k/ S. b" Y" I1. Will need Chem 22 (kidneys were functioning properly) prior to the start 7 T( M9 B, y) k! W
of supplementation.
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Myo Inositol 2gm twice a day （3/4 teaspoon powder 对应约2克 - 2gm）
) i; I9 c' ?. `8 n5 G: I2 jMelatonin 3 mg at bedtime (not for patient taking thyroid medication)' A5 S( R4 C$ S6 R! K* K% U( [+ X1 Q
Co Enzyme q10 200mg three times a day% T* L) q2 N. U0 t ]( i b
Omiga 3 fatty acid 500mg once a day+ c% K) d! [1 P$ v! \ P
Vitamin C 500mg once a day (Take in am)+ D4 k6 B3 [# A" e" R' v3 s
Vitamin E 200IU once a day7 p0 M" ~9 M( C1 A5 m7 U" {
L-arginine 1000mg twice a day; g& X* U: ]+ ?0 E/ @
Pycnogenol 100mg once a day
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& K0 U# T, v, d0 s& n7 a, s2. Stop with start of stimulation medications
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1 `$ I8 S$ h; \* T4 I+ m% [2 |【在哪里购买：仅供参考，不一定是最好选择】 t1 k! h# X t3 }
( g2 R7 n6 ?! x- ]! @/ c- ]$ M* G" r如果等不及shipping，可以先到Whole Foods买少量的，立马开始吃着，再到网上找deal。下面的厂家都是很好的，或者是不错的选择，每个牌子我都和业内的朋友核对过，可以放心：
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- "nature made" Prenatal + DHA @ Costco
" i; T& ^2 ^/ z, f* p' D6 ~- "Nordic Natural" (Ultra) Omega 3 @ Whole Foods6 b: j. D, i5 y. O# _
- "NOW" Inositol Powder @ amazon" e5 @# A; A2 m: t( P
- "nature made" CoQ10 @ Costo
O; f9 [) o$ d5 s- L-arginine (antioxidant); g% [$ z& I( O2 o
Twinlab L-Arginine 500mg, 100 Capsules (Pack of 3), S: O; b l" K( C
http://www.amazon.com/gp/product/B001G7QG7W/ref=ord_cart_shr?ie
6 Q: h s" Q m) E6 g- Pycnogenol (antioxidant)
3 }& a t3 M1 z3 @; O/ aGNC Preventive Nutrition Pycnogenol
% E/ I; g9 G* G9 r& H, j/ [+ |; _http://www.drugstore.com/qxp150135/gnc_preventive_nutrition/pyc
" m$ t9 x$ C' `: |# r/ g" Ohttp://www.gnc.com/search/index. ... pycnogenol&orig
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【补充说明】
4 S+ q0 ]$ M2 _/ u2 H/ T* P- 保健品里"nature made"应该是个好牌子
: C# e# i9 e. B4 M P- Prenatal+DHA (一定要有的，注意不要和钙片同时服用，钙影响身体对铁、镁等的吸
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- Omega 3 （建议买"Nordic Natural"，它家的用了真正的深海鱼）
/ o- v: m: k7 C8 l- Vitamin E9 }+ N& t0 ?2 B1 s6 ^6 o
- Vitamin C
! e, o7 F2 W$ U" Z7 O7 U* g2 _- 睡前吃calcium citrate和Melatonin（钙片最好睡前服用）
: j) v/ p* w* s$ c" X1 x6 P- Inositol Powder: Myo Inositol (Inositol)9 q$ x8 [$ N# \% H! d+ ^
Myo-inositol is one of nine distinct isomers of inositol, and the terms are & V- {" ]$ m- {( s. y
often used interchangeably.& b5 G1 V( {" z( s" ?* N
- CoQ10 ) E! ~5 [' ]" _
- Melatonin 会使TSH上升，有甲减的不要服用。5 i% ?' b7 }1 H4 O
- L-arginine (antioxidant)
) w7 S# i; v. N$ b" u# o" T8 f5 }- Pycnogenol (antioxidant)
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1 ^" w1 ?4 K" r3 {1 t8 Z【关于十全大补剂量】
3 m% g# I b1 U0 z- 记得Myo Inositol无害，可以大量服用，如果过于超量，它会随小便排除
/ @# U e: r/ w( ]2 k ? k( G$ R4 ihttp://mental-health.emedtv.com/inositol/inositol-overdose.html6 l. g8 N" l4 l7 \
Inositol is a naturally occurring molecule sometimes used in dietary / \1 t8 [) e% J" s% i
supplements. It is not known exactly what to expect with an inositol ; Y+ g8 E5 Q2 w! {& [6 f
overdose (or if an overdose is even possible).; M) _/ S- P# I. F
# A9 c- U5 f6 w2 I+ W% G- Vitamin C可以这样大量吃的；; }; f# t' i: l3 Q( L
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- Vitamin E是跟国内的妇产科医生double check，她也特意关照要加强补充的。
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9 I- c4 V8 r$ c4 W$ t- Co Enzyme q104 {* j7 l( Q( q+ |6 K4 V
http://heart-disease.emedtv.com/coq10/coq10-overdose.html( i j4 N, u+ X4 }5 k7 D2 d
similar to a vitamin and is naturally made in the body. 关于Overdose，尚不清
9 v7 E2 [6 x) t$ e; t* h1 I楚，只是说会有些副作用。但我身体没什么不好的感觉，就吃下去了。
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. ~) |1 F6 p3 H& v+ V: B$ [0 i- L-arginine ! w* m2 w$ x, ?
There is almost no information available about the possible symptoms of an L
7 l+ X' c% u3 H# e. Z: j6 s8 G-arginine overdose. 这个是抗氧化的，和蓝莓一个作用。也是说没啥害处，可能会有! ]) g$ @8 C1 w2 U. U7 U
副作用，恶心，闹肚子，但我这么大量吃也没有感觉。
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* y5 l8 T. ~0 J K3 y) l% `- Pycnogenol
. j r0 S3 Z" W' Z7 X- Xhttp://asthma.emedtv.com/pycnogenol/pycnogenol-overdose.html K) u# I4 C. h9 v% ~
The exact effects of a Pycnogenol overdose are not completely clear.
5 Y. S4 Q6 d+ @, | Q) G& D# ]Possible symptoms may include low blood pressure, low blood sugar, or an
+ n: ~' d! \' Q( E( g. c& H& E% Z) Pincreased risk of bleeding. The effects of an overdose will vary, based on
( p( L+ ?' I% h- v1 z. J, q. yhow much Pycnogenol was taken and whether it was taken with other substances
' O) X6 D; @6 H( q6 C) G. Treatment for a Pycnogenol overdose will most likely involve supportive ; ]' `/ [/ e$ s3 }: @2 X. n% q4 I
care.也是抗氧化的，也是没感觉到副作用，而且吃100mg，一点没过量。
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【各个阶段的服用指南】/ E& ^3 C1 e$ D" e, K9 Z
CCRM护士去年（2010）年底告诉我的，具体怎么服用大家领会精神，自由发挥吧：
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( m/ j5 |. Z5 `: n$ U***Before stim***
& p/ X9 a7 Y: I1 FMyo Inositol - 2 g x 2 / day
% l, N% l9 v: J- ?1 fCo Enzyme q10 - 800 mg x 1 / day
8 L& s4 P. C0 v# s; XPrenatal + DHA - 1 softgel / day
5 o/ \: w V+ C! M9 j3 POmiga 3 - 1 softgel / day
8 |5 K: I" x6 E: V7 KCalcium
) f$ \' I o( K) u7 q% oVitamin C! J; L$ f! @9 X, M4 B
Vitamin E
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***after stim***
8 u1 ~0 _: r Q: ~& J& X$ S. G" fPrenatal + DHA - 1 softgel / day
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***after ER***: p, R0 }. D- V% Z" l P
Prenatal + DHA - 1 softgel / day
$ U r$ M. h" P% sOmiga 32 Z0 G# I2 P% c' ^- D" C
Calcium
1 z- \5 J+ r- @0 S5 C: j" xVitamin C8 {7 h5 E$ C. |! }1 c, W7 E
Vitamin E 1 H# F# q, [& j; k0 X( n
4 P$ `2 |9 d! L O4 b1 y***before FET***
+ m# t b' o1 o* h1 @! PPrenatal + DHA - 1 softgel / day% i/ G3 V* N1 ]7 f( R
Calcium
) d0 s3 V8 o/ |$ p! nVitamin C
% L& o5 t& G/ w$ n" DVitamin E ' P7 }* O% d4 r# b5 n' ^
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***after FET***% G3 R+ t8 j4 q% U4 [8 W$ ^2 v F
Prenatal + DHA - 1 softgel / day. [4 t) h0 | }9 f, ~
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) j4 [! x; ^! A$ K, }6 a【关于十全大补的典故】( T6 D8 B' ^! _6 @# V2 s8 D6 {( j% T
http://forums.fertilitycommunity.com/vitro-fertilization-ivf/202 t5 c7 p n! b& _# R" a8 W
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When I met Dr. Schoolcraft he shared a story with me. For a while he has been treating a 44 year old woman from Europe and each IVF cycle she only produced a few eggs however none of them developed into a normal embryos. So this time she comes for another IVF treatment and this cycle she has 9 HEALTHY EMBRYOS. He said he jumped in his chair he couldn’t believe it and asked her what did she do? She admitted taking for 4 months well known in Europe supplement “Inofolic plus”. He said that we here in US don’t have this supplement however he researched it and found out contents of “Inofolic plus” and from now on he recommends it to all his poor responders including me. He recommends taking it at least 3 months prior to retrieval or prior next IVF cycle but it you want to take it longer it is up to you. / E5 j+ J6 @& q
d3 }9 n9 A5 p3 s' V( QAzalia My AMH is also very low it is 0.2 and I think this is as low as you can get next one is simply zero. This is what he put me on:: v+ R9 o% \- c4 }9 Y2 f4 c
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Myo Inositol 2 gm take twice a day (they have different forms pills, capsules, for myself I found a powder and take it in a form of powder - just decided less pills to swallow) 7 c, H5 m8 w6 y* X
Melatonin 3 mg take at bed time (will make you sleepy)8 n k D" B) \- H8 T5 t
Co Enzyme q10 200 mg take twice a day (I bought a brand that has chewable pills, can’t stand to swallow pills I always prefer powder, liquids or chewable of course if I can find one)
8 g) U* x: s$ b2 p2 m+ ^" @% W0 K7 pFolic Acid 1 mg take once a day
u) n: H0 }* r* v2 W$ q% p. ?. u* wDHEA 75 mg take once a day (it comes in 25 mg tablets I take 2 tablets in the morning and one at night).
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5 u4 S, q% m- Q+ W6 c3 B' U, ZHe instructed me to stop it with the start of stimulation medications.
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$ K$ j8 [5 G+ I0 ?5 M【其它深度讨论贴】
1 n* H* p0 @( f, G3 O8 Jhttp://www.mitbbs.com/clubarticle_t1/IVF/31229539_0_1.html |
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发表于 2012-1-5 03:09:20
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