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Beer 中心转抄来的关于丈夫DQ alpha 201的资料
# _( \) f( z5 o9 Q n' F+ q" b"A. DQ Alpha3 {/ q q$ V( u d' F4 {
This test measures whether the DNA of the couple is too closely matched. These tests give you2 S" U3 p( {, d/ o4 g
back two numbers for both members of the couple. In a normal pregnancy the father's DNA in4 x* _5 K* X, i
the baby tells the mother's body to set up a protective reaction around the developing embryo. If) t- X* j% n U4 s$ z9 L, M
the father's DNA is too closely matched to the mother's, there is a good chance that the embryo" z) }% ^* |* {7 S% K4 W7 Q+ D1 W
created by them is unable to differentiate itself from the mother's body. The mother's body then
. K& [+ A( W9 [ Mrejects the embryo because it cannot identify the embryo as a baby.
( D6 p b( o: M( B3 _4 RThere are two different tests for the DQ, the Alpha and the Beta test. Most patients are only: D0 x3 z3 s+ B/ J& x5 p
tested for the Alpha. The mother-to-be and the father-to-be get back two numbers (1.1, 1.2, 1.3,* \; Q+ f( X9 _$ M
1.4, 2, 3 or 4) one each from each of their respective parents (the baby-to-be's grandparents).
! T" J8 ?8 ]* Z; h% B9 x: xAlthough there are breakdowns of the 2's, 3's and 4's, many people find that only the 1's are
3 }1 N/ ?! L( X z7 s/ Msignificant, so they break those down to one more decimal. If both the mother-to-be's and the
; P" @; C) J8 hfather-to-be's DQ Alpha come back with a 4 DQ Alpha or the father-to-be's DQ Alpha comes
) Q! E9 k: L- i, K' x0 \back with a 2, a DQ Beta test is run. A DQ Alpha 2 translates into a DQ Alpha 201. The DQ1 ^/ E) c7 d% v# _7 B# T* i
molecule also has a beta chain, and when the DQ Beta is 201, then this sperm will only produce7 c) W" m5 m6 N
a placenta, and not a baby. 89% of the people who test APA positive either have DQ Alpha 4 or
6 w. @' i0 t$ G& pclosely matched DQ Alphas between partners. DQ Alpha compatibility is seen between mother
2 n+ k' a5 c% [ Z5 h0 f. [and pregnancies that failed (through IVF failure or recurrent pregnancy loss). DQ incompatibility
- h7 I/ @! j7 q. X+ Q3 G* ?between mother and baby was far more common in women successfully delivering babies.
2 n8 B% Z3 x: P- @0 I2 kDQ 201: If the father-to-be has a 2 in his DQ Alpha, 2% of the time a DQ Beta will show that it, p% L2 ?& \4 R
is also a DQ 201. Since the DQ 201 father-to-be has two DQ numbers, if only one of his
+ a- u$ i& g, W8 M+ |& i; snumbers is the DQ 201, he has a 50/50 chance of producing an embryo that is DQ 201. If both of0 b1 d/ `4 @. `3 H
his numbers, both Alpha and Beta come back as 201, he has a 100% chance that all of his
) T* }9 O/ Q; w5 p' Dembryos will become blighted ova. The cure for this, when only one of his numbers is 201, is to
8 N2 i0 i, X( p% r- w0 yput back more embryos to see if you can produce an embryo that is not DQ 201. If he has both% y, H/ N2 Z, n \5 F
numbers come back as a 201, the only option is donor sperm. 100% of DQ 201 embryos become/ C" D1 _1 {4 a! Z% X* J" y
blighted ova." |
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发表于 2011-5-12 23:59:52
