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Beer 中心转抄来的关于丈夫DQ alpha 201的资料
! Q6 W! N# U, U8 f"A. DQ Alpha
" v X1 ?1 Q1 q: VThis test measures whether the DNA of the couple is too closely matched. These tests give you
7 ~8 a$ E) `9 ]6 w4 R4 I6 Vback two numbers for both members of the couple. In a normal pregnancy the father's DNA in% W2 A; h* l# a9 E
the baby tells the mother's body to set up a protective reaction around the developing embryo. If
+ j6 M7 F3 u7 ]2 P4 [' \$ U5 @the father's DNA is too closely matched to the mother's, there is a good chance that the embryo `8 Q% {0 `) h4 z1 h1 a
created by them is unable to differentiate itself from the mother's body. The mother's body then9 F2 g, ?" J4 \9 N6 ?3 k
rejects the embryo because it cannot identify the embryo as a baby.- \, t4 Z3 Q3 ~- `2 A9 \+ o
There are two different tests for the DQ, the Alpha and the Beta test. Most patients are only
( {3 C' v1 h( n8 Mtested for the Alpha. The mother-to-be and the father-to-be get back two numbers (1.1, 1.2, 1.3," c; i& C5 ~& R2 X. w! A. w
1.4, 2, 3 or 4) one each from each of their respective parents (the baby-to-be's grandparents).
. W( L9 d9 g3 [. G# nAlthough there are breakdowns of the 2's, 3's and 4's, many people find that only the 1's are" t* J8 d1 i, n% h( m* l
significant, so they break those down to one more decimal. If both the mother-to-be's and the# x6 H" o+ |/ S! N
father-to-be's DQ Alpha come back with a 4 DQ Alpha or the father-to-be's DQ Alpha comes
2 f( |3 K. J9 @back with a 2, a DQ Beta test is run. A DQ Alpha 2 translates into a DQ Alpha 201. The DQ
" a: N# ~1 w, H* C% s; Umolecule also has a beta chain, and when the DQ Beta is 201, then this sperm will only produce
6 s3 ~! K% F% Ma placenta, and not a baby. 89% of the people who test APA positive either have DQ Alpha 4 or
9 ]/ t/ ~0 a% T. ~# I1 Vclosely matched DQ Alphas between partners. DQ Alpha compatibility is seen between mother0 I7 G @' k0 j2 C$ }% H
and pregnancies that failed (through IVF failure or recurrent pregnancy loss). DQ incompatibility
6 T m( t3 l. S6 R$ O0 }( Sbetween mother and baby was far more common in women successfully delivering babies.
6 U# ~; }# ~+ K/ V7 a$ P) U8 ^DQ 201: If the father-to-be has a 2 in his DQ Alpha, 2% of the time a DQ Beta will show that it
8 Q( t% w5 i: `4 jis also a DQ 201. Since the DQ 201 father-to-be has two DQ numbers, if only one of his P3 J7 T7 @- N/ {7 l
numbers is the DQ 201, he has a 50/50 chance of producing an embryo that is DQ 201. If both of, g) F- V5 u# w
his numbers, both Alpha and Beta come back as 201, he has a 100% chance that all of his. G, x: d6 W5 _5 j
embryos will become blighted ova. The cure for this, when only one of his numbers is 201, is to
l& n h" q7 u8 S8 U" w3 ^, V8 Gput back more embryos to see if you can produce an embryo that is not DQ 201. If he has both
" `9 t2 h2 |+ m& _+ {% Snumbers come back as a 201, the only option is donor sperm. 100% of DQ 201 embryos become3 L; {' Z) t' F9 e+ L' l: h
blighted ova." |
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发表于 2011-5-14 18:07:00
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