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一位美国病人的不孕治疗经历
这是从老美论坛里抄来的帖子 # ~1 H: x1 ~: r @
- v7 p: f9 A4 Y3 `" q% |5 V我从未怀过孕 – 自然的也好，人工授精也好，试管也好，从未成功过，后来做赠卵，也不成功，连着床一次都没有过。我们几乎都要放弃了，后来听到免疫不孕这么一说，就去做了检查，结果我的NK细胞活性过高。
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$ u* z' y1 e M4 @我决定再做最后一次赠卵试管尝试，那时我已经43岁。尽管我做自卵试管时卵子质量、胚胎质量看上去都很好，医生仍建议我做赠卵，因为年纪大了，卵子不正常的几率太高了。
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我在移植前2个星期打了一次免疫球蛋白，剂量40g。开奖好孕了，怀了双胎，其中一个停育了，生下一个女儿。验血查出怀孕后，我又连打了三次免疫球蛋白，每次剂量20g，第一次是在开奖的当天，以后两次是每隔4个星期。四次免疫球蛋白一共花了我1万美元。 8 J, j( o# g7 p; g) y6 k
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后来我又做冷冻移植，还是按前面的方案打免疫球蛋白，又怀孕了，现在已经11周。这次我只打三次免疫球蛋白，省掉了最后一次的20g一针，所以这回的费用是8000美元。
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I couldn't get pg to save my life -- not naturally, IUIs, GIFTs with my eggs, IVFs with my eggs, and finally DE -- nothing, not a single positive beta. We were about to give up but had heard about immune system testing, and I came out positive for elevated NK cells.
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Decided to try one more time, and stayed with DE since I was 43, even though I had been having good results with my own eggs -- decent numbers, good-looking embryos. The doctor suggested because of my age not to go back to my eggs, so we went DE again. $ t$ K+ ^# w6 _/ p. M7 ]0 ^: U
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Had an IVIg treatment two weeks before transfer (40 gr - comes out to about $1,000/10 gr). Got pg, had twins and then a vanishing. DD is 4 years old.
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$ P7 c: Z7 s0 `! X3 BI had to have another IVIg (20 gr) right after positive beta, then two more (20 gr/each) for a total of four treatments, all spaced four weeks apart. Total cost, not covered by insurance, about $10,000 in the US.
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Decided to try for a sibling. Same protocol exactly, different donor. Got pg, had twins who just turned two. Another $10,000. Cha-ching.
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Decided to use our last frozen embies this year, same IVIg protocol, got pg. Am almost 11 weeks, and had last IVIg treatment two weeks ago. This time, they only said I had to do three -- I think they have decided that four was not necessary, esp given the expense. So this cycle was "only" $8,000 for the IVIg (40/20/20).
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As you can see, I am a true believer -- it was not just DE that ended up working, because it DIDN'T work the first time, from a very fertile woman (has five kids from two husbands!) It was only after I went to IVIg that I got pg -- three tries out of three, with two different donors! |
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