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Beer 中心转抄来的关于丈夫DQ alpha 201的资料
# n, y& e2 W7 T* o"A. DQ Alpha* _4 {+ S8 t. Q8 |( \8 L) e; }6 q2 ]2 W
This test measures whether the DNA of the couple is too closely matched. These tests give you
u! R+ J' `! x0 `5 e. A7 Dback two numbers for both members of the couple. In a normal pregnancy the father's DNA in
% _7 Z/ F6 K3 L/ }6 O" {the baby tells the mother's body to set up a protective reaction around the developing embryo. If
) z9 f! n) I' e# L1 [$ g1 Rthe father's DNA is too closely matched to the mother's, there is a good chance that the embryo
9 ~' ~7 K6 x& ]created by them is unable to differentiate itself from the mother's body. The mother's body then
- i. Z' y; _+ |7 Prejects the embryo because it cannot identify the embryo as a baby.) z" L( n+ Y6 k' y
There are two different tests for the DQ, the Alpha and the Beta test. Most patients are only
* R7 c: Y1 P. I! ?tested for the Alpha. The mother-to-be and the father-to-be get back two numbers (1.1, 1.2, 1.3,
1 b: A5 ]- f" n3 F+ v1 ?1.4, 2, 3 or 4) one each from each of their respective parents (the baby-to-be's grandparents).
" L1 n, a& e6 PAlthough there are breakdowns of the 2's, 3's and 4's, many people find that only the 1's are
% Z$ _. j$ X! {$ u; n, ysignificant, so they break those down to one more decimal. If both the mother-to-be's and the
% T4 K+ J* ]6 r- l3 Qfather-to-be's DQ Alpha come back with a 4 DQ Alpha or the father-to-be's DQ Alpha comes
4 Z2 m% ~# D) t- \2 M8 @back with a 2, a DQ Beta test is run. A DQ Alpha 2 translates into a DQ Alpha 201. The DQ- k& c% Q3 l, Q# u
molecule also has a beta chain, and when the DQ Beta is 201, then this sperm will only produce" R0 D+ y" R R' `- \2 Q4 g
a placenta, and not a baby. 89% of the people who test APA positive either have DQ Alpha 4 or
0 p6 A$ U0 n! N- S. w$ Bclosely matched DQ Alphas between partners. DQ Alpha compatibility is seen between mother
2 l5 d0 x6 E3 q$ @ B* O. fand pregnancies that failed (through IVF failure or recurrent pregnancy loss). DQ incompatibility
4 S, }" R' z2 M6 O' gbetween mother and baby was far more common in women successfully delivering babies.
i# B2 e9 n( T3 YDQ 201: If the father-to-be has a 2 in his DQ Alpha, 2% of the time a DQ Beta will show that it5 d9 m3 k/ f; G- N6 D# _3 J2 F
is also a DQ 201. Since the DQ 201 father-to-be has two DQ numbers, if only one of his9 v- P8 A B3 {) w
numbers is the DQ 201, he has a 50/50 chance of producing an embryo that is DQ 201. If both of2 f5 ?/ p% ]6 ]
his numbers, both Alpha and Beta come back as 201, he has a 100% chance that all of his
^( C5 @- B6 o J/ Y5 nembryos will become blighted ova. The cure for this, when only one of his numbers is 201, is to
$ q* O5 R1 \, N, |- L; ^put back more embryos to see if you can produce an embryo that is not DQ 201. If he has both& `# P9 H% ?3 F% Q/ u1 t
numbers come back as a 201, the only option is donor sperm. 100% of DQ 201 embryos become: A& q- h# \, g) N$ b
blighted ova." |
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发表于 2011-5-14 18:07:00
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